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Squalene

Addtime:2023-08-28 Hit: 1031

Squalene (C30H50) is an unsaturated hydrocarbon found in animals and some plants, and is a precursor of steroids. The IUPAC name of squalene is 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene (MW = 410.7).

CAS number: 111-02-4

CDE registration number: F20180000667

Pharmacopoeia specification compliance: EP

Storage: In an airtight container, protected from light, at 2 ~ 8 .

 

Properties and Benefits

Using advanced refining and purification technology, the impurities in the product are significantly reduced.

Low peroxide value and acid value, provide good storage stability.

Bacterial endotoxins and micro-organisms are strictly controlled, meet the requirements of parenteral dosage forms.

 

Applications

Main component of skin surface polyunsaturated lipids, natural softener, moisturizer and antioxidant.

Squalene is the core ingredient in vaccine adjuvant MF59, which can enhance the immunogenicity of the vaccine.

The MF59 emulsion was prepared with squalene, polysorbate 80 (For Injection), sorbitan trioleate, etc. through high-speed shearing and high-pressure homogenization, the product obtained has the same particle size as the RLD product and shows good accelerated and long-term stability.




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